Supply 98% Ascorbyl Tetraisopalmitate VCIP CAS 183476-82-6
Ascorbyl Tetraisopalmitate: Powerful Antioxidant
Ascorbyl Tetraisopalmitate, also known as VCIP or Vitamin C Tetraisopalmitate, is a light yellow to colorless liquid. It is an esterified vitamin C derivative and the most valuable of these. It is oil-soluble, boasts excellent transdermal absorption, and is stable to light and heat. Upon transdermal absorption, it is converted into vitamin C in skin cells, exhibiting its active vitamin C properties. It penetrates the skin, converts to vitamin C, and exerts its effects (hence its name, vitamin C inducer). It has excellent oil solubility and dissolves broadly and rapidly in esters, vegetable oils, ethanol, and hydrocarbons (excluding polyols). It is also mild and non-irritating, making it suitable for sensitive skin.
As a new-generation, fat-soluble vitamin C derivative, ascorbyl tetraisopalmitate (VCIP) not only overcomes the stability challenges of standard vitamin C but also demonstrates exceptional whitening, anti-aging, and anti-inflammatory properties, making it a preferred whitening ingredient for many high-end skincare brands.
① Enhanced Stability: Transformed from an antioxidant that is "light-sensitive" (and thus rendered ineffective upon light exposure) into one that can be used with complete confidence during the daytime;
② Improved Skin Affinity: Evolved from water-soluble Vitamin C into the oil-soluble derivative VCIP, allowing for significantly easier transdermal absorption;
③ Greater Gentleness: Shifted from a distinctly acidic formulation—prone to causing irritation—to a gentle version suitable even for sensitive skin. Once absorbed, VCIP is converted back into its active form—pure Vitamin C—through the action of esterases within the skin. Tests conducted on skin models demonstrate a conversion rate as high as 84%, resulting in a significant improvement in overall utilization efficiency.

YTBIO: Providing High-Quality Ascorbyl Tetraisopalmitate and Services
High-quality nutritional supplements are crucial to your health journey. YTBIO specializes in providing high-quality Ascorbyl Tetraisopalmitate.
Why choose YTBIO? We hold the following certifications:
- cGMP, ISO9001, and ISO22000 certifications ensure rigorous quality control throughout the entire process;
- BRC and HACCP system certifications ensure product safety and reliability;
- EU and NOP organic, kosher, and halal certifications meet various global standards and dietary requirements.
We specialize in the research, development, and production of natural plant extracts, cosmetic active ingredients, and health foods. We primarily produce plant extracts, health food ingredients, and a variety of end-use products, including capsules, softgels, granular capsules, gummies, tablets, and solid beverages. Our production facilities and equipment meet national standards, and our production processes strictly adhere to GMP requirements. If you have any questions, please feel free to contact us at sales@sxytbio.com
|
Specifications
|
Results
|
|
|
Appearance
|
White Powder |
Confirm
|
|
Odor& Taste
|
Characteristic
|
Confirm
|
|
Loss on drying
|
≤8.0%
|
2.8%
|
|
Assay(HPLC)
|
99.0% min
|
99.2%
|
|
Ash
|
≤1.0%
|
0.35%
|
|
Heavy Metal
|
≤10 ppm
|
Confirm
|
|
As
|
≤1.0ppm
|
Confirm
|
|
Pb
|
≤1.0ppm
|
Confirm
|
|
Cd
|
≤1.0ppm
|
Confirm
|
|
Hg
|
≤0.1ppm
|
Confirm
|
|
Total plate count
|
≤1000 cfu/g
|
Confirms
|
|
Yeast&Mold
|
≤100 cfu/g
|
Confirms
|
|
E.Coli
|
Negative
|
Negative
|
|
Salmonella
|
Negative
|
Negative
|
|
Staphylococcus aureus
|
Negative
|
Negative
|
Features of Ascorbyl Tetraisopalmitate
High Stability
VCIP has no antioxidant properties on the skin's surface, but it is able to exert its effects once inside cells. It is highly stable and resistant to deterioration.

High Transdermal Absorption
VCIP is a fat-soluble ingredient, making it more readily absorbed into the skin compared to the water-soluble form of vitamin C. Furthermore, in simulated skin tests, the conversion rate of VCIP to vitamin C reached an impressive 84%.
High Mildness
VCIP is mildly irritating to the skin and generally does not cause irritation even on sensitive skin, making it suitable for a wide range of skin types. Even sensitive skin types do not need to worry about developing tolerance.
High Efficiency
VCIP's high efficacy stems from its fat-soluble nature, allowing it to be effective even at low concentrations, resulting in a high conversion rate.

Differences between VCIP and VC
VC: VC has antioxidant effects, promotes collagen regeneration, and inhibits melanin production. However, it has poor transdermal permeability and is unstable, easily deactivated and prone to oxidative discoloration. It is not very friendly to sensitive skin and difficult to incorporate into cosmetics.
VCIP: VC is a more stable and gentle VC derivative. Its oil-soluble properties allow for better transdermal permeability and rapid absorption. It can be used safely even on sensitive skin without the risk of developing a tolerance.
Compared to traditional vitamin C, VCIP offers greater stability, enhanced transdermal absorption, and oil-soluble properties. During skin absorption, VCIP is converted to vitamin C, exerting its benefits, including skin brightening, promoting collagen synthesis, and inhibiting lipid peroxidation.
Skincare Benefits of Ascorbyl Tetraisopalmitate
Whitening
VCIP, when used in cosmetics, has excellent transdermal absorption properties and can inhibit intracellular tyrosinase activity and melanin production. Foreign researchers have evaluated the effects of VCIP on ultraviolet (UV)-induced skin pigmentation and found that topical application significantly inhibited the increase in intracellular peroxides after UVB irradiation and enhanced cellular tolerance to reactive oxygen species.
Antioxidant Effects
As a cosmetic ingredient, VCIP inhibits lipid peroxidation, similar to vitamin C. It is readily absorbed by the skin, preventing lipid peroxidation and skin aging.
Anti-Aging Effects
VCIP breaks down into free vitamin C in the skin to perform its physiological functions. As a powerful antioxidant, vitamin C effectively neutralizes free radicals, thereby improving skin texture, reducing elastin deposition associated with photoaging, and promoting collagen synthesis.
Currently, many skincare brands have begun using VCIP as a primary ingredient, particularly in the whitening and anti-aging sectors. VCIP, with its primary ingredient, has formed a comprehensive product line, from cleansers to essence creams. Furthermore, by combining it with other whitening ingredients like niacinamide and arbutin, VCIP's whitening effects are further enhanced, making related products more competitive and attractive in the market.

FAQ
Q: What certifications do you hold?
A: We prioritize product quality and safety, and our production facilities hold several top international certifications, including:
· cGMP
· ISO9001 and ISO22000
· BRC
· HACCP
· EU and NOP organic certifications
· Kosher certification
· Halal certification
Q: Do you provide third-party test reports (COAs) for your products?
A: Of course. We provide a COA with every batch.
Q: Do you offer custom products and technical support?
A: Yes, we have a strong R&D team. In addition to standard products, we can also provide customized dosage forms and customized packaging to meet your specific needs.
Our technical team is always ready to provide comprehensive technical support, including product application and formulation advice.
Q: What other related products do you have?
A: Yes, we have a wide range of cosmetic raw materials, including:
Whitening ingredients: Niacinamide, Vitamin C and its derivatives, Arbutin, Tranexamic acid, Kojic acid and its derivatives, Plant extracts (such as Glabridin, Olive Fruit Extract, Centella Asiatica Extract, etc.)
Anti-aging ingredients: Retinol, Peptides (such as Oligopeptide-1, Oligopeptide-68), Bosin, Astaxanthin, GABA, Ectoin, etc.
Email: sales@sxytbio.com
WhatsApp/phone: +86 17782577059








